otic vesicle การใช้

Parts of the otic vesicle in turn form the vestibulocochlear nerve.
BMP4 is found in early embryonic development in the ventral marginal zone and in the eye, heart blood and otic vesicle.
The general sequence in formation of the otic vesicle is relatively conserved across vertebrates, although there is much variation in timing and stages.
Patterning during morphogenesis into the distinctive inner ear structures is determined by homeobox transcription factors including PAX2, DLX5 and DLX6, with the former specifying for ventral otic vesicle derived auditory structures and the latter two specifying for dorsal vestibular structures.